The Agenbite of Inwit

Nietzsche asked what our conscience tells us...there's a sting to it, yes, but why? A sting...like a yellowjacket that we've angered, come too close to its nest, crossed over some invisible line that separates its world from ours...there is something like this in Nietzsche's assesment. There are conditions for our preservation wrapped up in the movement of our bodies, the judgments and thoughts we engage in, the things we eat, and the people we love and hate. When we cross the boarder of these conditions the sting is harsh, but we can overcome it. That is what the 'over-man' is, the over-coming of these boarders, the creation or formation of conditions for life...the problem is when we are reactive to the conditions, rather than actively forming them.

But "objectively" we really can't create our own conditions, because even our need for creation is a condition for the preservation of life. What is Nietzsche's answer? The Eternal Recurrance of the Same. The Gay Science, section 341:

The heaviest weight. -What if some day or night a demon were to steal into your loneliest loneliness and say to you: 'this life as you now live it and have lived it you will have to live once again and innumerable times again; and there will be nothing new in it, but every pain and every joy and every thought and sigh and everything unspeakably small or great in your life must return to you, all in the same succession and sequence...the eternal hourglass of existence is turned over again and again, and you with it, speck of dust!'

To affirm every moment as if (one can sense a little of the Saint Paul as if here) one were to live it over and over and over. This isn't about getting rid of guilt. For Nietzsche, the problem is that we are too innocent, since we do everything because of the conditions for the preservation of life. No, the problem is: how can I be responsible.